Effect of 8 week resistance training on adiponectin, Insulin resistance, insulin sensivity and HbA1c levels in overweight men

Introduction Physical activity is the most important factors of energy consumption in humans. Since energy absorption can regulated the adiponectin expression positively or negatively. Also, altering energy consumption with exercise may affect the adiponectin levels. Therefore, the present study aimed to the effect of 8 weeks resistance training on adiponectin, insulin hemostasis and HbA1c levels in overweight men. Materials & Methods In this semi-experimental study, total of 22 overweight young healthy men (BMI 28.76±0.96 and age 31.31±2.23) were randomly assigned to control (n=11) and resistance exercise (n=11) groups. Subjects in the resistance exercise groups participated on 8-week exercise training programme with 55-75% of 1RM for three sessions per week. Anthropometric indices (weight, body fat percentage, BMI) were analyzed. Insulin, glucose, adiponectin, HbA1c and HOMA-IR were assessed from fasting blood samples before and after the 8-week exercise programme. Data were analyzed by t-test. Results Resistance training led to decrease in Anthropometric indices (P<0.05), insulin levels (P=0.001) and HOMA-IR (P=0.004) and increase adiponectin (P<0.001) and QUICKI (P=0.025). But changes in glucose (P=0.201) and HbA1c (P=0.686) levels was not significant. Conclusion Considering to the effects of resistance exercise on Adiponectin levels and body composition, it seems that participation in this type of exercise, can improve insulin sensitivity and weight reduce, also an important factor in controlling and preventing the overweight-related diseases.